23+ hour, 21+ min ago   (75+ words) A new comprehensive review published in the Journal of Nanoparticle Research surveys one of the most quietly promising corners of nanomedicine: carbon dots, nanoscale specks of carbon that are showing remarkable ability to kill bacteria and dismantle the sticky biofilms…...

23+ hour, 24+ min ago   (521+ words) Bacteria are famous for forming patterns, from the concentric rings of Proteus colonies to the branching networks that motile microbes paint across agar plates. Now researchers at Columbia University have turned one of biology’s most familiar workhorses, Escherichia coli, into…...

23+ hour, 24+ min ago   (80+ words) Bacterial wilt, caused by the soil-borne pathogen Ralstonia solanacearum, is one of the most destructive plant diseases in the world, striking tomatoes, potatoes, bananas and hundreds of other crops. Once the bacterium establishes itself in a field, it is notoriously…...

1+ day, 1+ hour ago   (72+ words) Hypoxia-inducible factor 1 alpha, or HIF1α, has long been celebrated as the master switch that allows cells to sense and survive low-oxygen conditions, a discovery that earned the 2019 Nobel Prize in Physiology or Medicine. In the intestine, this transcription factor is far…...

1+ day, 1+ hour ago   (97+ words) A root long used in traditional East Asian medicine is now giving up its chemical secrets to modern analytical science. Researchers at Kyungpook National University, working with a collaborator at the University of California, Davis, have carried out an integrated…...

1+ day, 1+ hour ago   (661+ words) A single protein called BAX sits at the gateway between life and death for human cells. When tissues are injured, stressed, or deprived of oxygen, BAX springs into action, punching holes in the outer membrane of mitochondria and triggering the…...

1+ day, 1+ hour ago   (485+ words) A sprawling review of the meadow rue genus, Thalictrum, has catalogued a striking trove of biologically active plant chemicals across Africa and Asia, while simultaneously exposing how little of the evidence stands up to rigorous scientific scrutiny....

1+ day, 1+ hour ago   (682+ words) A study that promised a new way to deliver the asthma drug salbutamol sulphate through gelatin-based swellable hydrogels has been struck from the scientific record....

1+ day, 1+ hour ago   (120+ words) Adoptive T cell therapy has delivered striking remissions in some blood cancers, but its promise in solid tumors has been repeatedly undermined by a stubborn problem: the therapeutic cells do not last. Engineered T cells that flood a tumor and…...

1+ day, 1+ hour ago   (55+ words) Gene editing has long promised a revolution in cancer medicine, yet the promise has remained stubbornly out of reach for one deceptively simple reason: getting the CRISPR-Cas9 machinery into tumor cells, and only tumor cells, is extraordinarily difficult. A new…...